Colon | Rectum | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Tumour subgroups | HRT use | n | HR crude | p | HR adjusted | p | n | HR crude | p | HR adjusted | p |
beta-catenin + | No | 68 | 1.00 | 1.00 | 51 | 1.00 | 1.00 | ||||
ERT | 9 | 1.62(0.80-3.26) | 0.180 | 1.52(0.74-3.16) | 0.257 | 4 | 0.38(0.14-1.09) | 0.073 | 1.00(0.45-2.25) | 1.000 | |
CHRT | 11 | 0.88(0.46-1.67) | 0.696 | 0.96(0.48-1.91) | 0.910 | 8 | 0.44(0.19-1.02) | 0.054 | 1.00(0.44-2.26) | 1.000 | |
beta-catenin − | No | 64 | 1.00 | 1.00 | 17 | 1.00 | 1.00 | ||||
ERT | 4 | 0.76(0.27-2.09) | 0.588 | 0.71(0.25-1.97) | 0.506 | 3 | 0.87(0.24-3.12) | 0.833 | 1.00(0.27-3.73) | 1.000 | |
CHRT | 10 | 0.91(0.46-1.78) | 0.779 | 0.92(0.45-1.88) | 0.808 | 3 | 0.41(0.09-1.83) | 0.242 | 1.00(0.25-3.95) | 1.000 | |
cyclin D1 + | No | 120 | 1.00 | 1.00 | 50 | 1.00 | 1.00 | ||||
ERT | 10 | 1.04(0.54-1.98) | 0.917 | 0.96(0.49-1.86) | 0.895 | 6 | 0.56(0.23-1.34) | 0.189 | 0.44(0.17-1.14) | 0.091 | |
CHRT | 18 | 0.86(0.52-1.42) | 0.557 | 0.95(0.56-1.62) | 0.854 | 11 | 0.60(0.28-1.28) | 0.188 | 0.51(0.21-1.24) | 0.135 | |
cyclin D1 − | No | 15 | 1.00 | 1.00 | 16 | 1.00 | 1.00 | ||||
ERT | 3 | 2.05(0.59-7.10) | 0.260 | 2.34(0.65-8.44) | 0.196 | 1 | 0.37(0.05-2.81) | 0.334 | 0.28(0.03-2.27) | 0.232 | |
CHRT | 4 | 1.33(0.44-4.05) | 0.615 | 1.50(0.46-4.94) | 0.504 | 1 | 0.19(0.02-1.56) | 0.124 | 0.07(0.01-0.88) | 0.039 | |
p53 + | No | 54 | 1.00 | 1.00 | 40 | 1.00 | 1.00 | ||||
ERT | 6 | 1.38(0.59-3.24) | 0.454 | 1.27(0.53-3.02) | 0.588 | 5 | 0.54(0.21-1.41) | 0.208 | 1.00(0.43-2.35) | 1.000 | |
CHRT | 9 | 0.94(0.46-1.92) | 0.869 | 1.02(0.48-2.20) | 0.951 | 9 | 0.56(0.25-1.27) | 0.168 | 1.00(0.42-2.40) | 1.000 | |
p53 − | No | 82 | 1.00 | 1.00 | 26 | 1.00 | 1.00 | ||||
ERT | 7 | 1.02(0.47-2.21) | 0.968 | 0.95(0.43-2.11) | 0.903 | 2 | 0.47(0.11-2.02) | 0.308 | 0.23(0.05-1.18) | 0.078 | |
CHRT | 13 | 0.89(0.49-1.61) | 0.703 | 1.00(0.54-1.86) | 0.996 | 3 | 0.36(0.09-1.54) | 0.170 | 0.19(0.04-0.96) | 0.044 | |
MSI | No | 36 | 1.00 | 1.00 | 2 | 1.00 | 1.00 | ||||
ERT | 1 | 0.36(0.05-2.67) | 0.320 | 0.28(0.04-2.08) | 0.212 | 0 | - | - | |||
CHRT | 5 | 0.84(0.32-2.16) | 0.710 | 0.90(0.34-2.40) | 0.832 | 0 | - | - | |||
MSS | No | 97 | 1.00 | 1.00 | 64 | 1.00 | 1.00 | ||||
ERT | 11 | 1.35(0.72-2.53) | 0.349 | 1.36(0.71-2.60) | 0.352 | 7 | 0.54(0.24-1.22) | 0.138 | 1.00(0.49-2.03) | 1.000 | |
CHRT | 17 | 0.98(0.58-1.65) | 0.943 | 1.08(0.62-1.89) | 0.789 | 11 | 0.46(0.22-0.97) | 0.041 | 1.00(0.49-2.05) | 1.000 |