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Table 3 Univariate and multivariate survival analyses by pN stage in patients with pT2 stage CC

From: Solitary lymph node metastasis is a distinct subset of colon cancer associated with good survival: a retrospective study of surveillance, epidemiology, and end-results population-based data

 

Univariate analysis

Multivariate analysis

Variable

5-year CCS

Log rank χ 2test

P

HR (95% CI)

P

Years of diagnosis

 

30.763

<0.001

 

<0.001

 1988-1993

90.9%

  

Reference

 

 1994-1999

92.0%

  

0.903 (0.789-1.033)

 

 2000-2003

93.6%

  

0.727 (0.637-0.830)

 

Sex

 

27.577

<0.001

 

<0.001

 Male

91.8%

  

Reference

 

 Female

93.5%

  

0.734 (0.664-0.812)

 

Age

 

77.274

<0.001

 

<0.001

 <60

95.4%

  

Reference

 

 ≥60

91.5%

  

1.823 (1.612-2.061)

 

Race

 

35.396

<0.001

 

<0.001

 White

92.8%

  

Reference

 

 Black

89.6%

  

1.517 (1.306-1.762)

 

 Othera

94.9%

  

0.692 (0.558-0.858)

 

Grade

 

4.629

0.099

 

NI

 High/moderate

92.9%

    

 Poor/anaplastic

90.9%

    

 Unknown

91.4%

    

Histotype

 

0.190

0.663

 

NI

 Adenocarcinoma

92.9%

    

Mucinous/signet ring cell

92.5%

    

No. of LNs dissected

 

20.732

<0.001

 

<0.001

 <12

91.7%

  

Reference

 

 ≥12

94.0%

  

0.846 (0.761-0.941)

 

LNs status

 

223.132

<0.001

 

0.002

 N0

94.2%

  

0.485 (0.423-0.556)

 

 N1a

87.2%

  

Reference

 

 N1b

83.8%

  

1.270 (1.060-1.521)

 
  1. aOther includes American Indian/Alaska native, Asian/Pacific Islander, and unknown.
  2. NI: not included in multivariate survival analyses.