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Figure 5 | BMC Cancer

Figure 5

From: The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas

Figure 5

Relationship between ribosome biogenesis and rDNA methylation differences in tumor-normal tissue pairs. (A) For each normal-tumor tissue pair, DNA methylation differences were calculated and subjected to hierarchical clustering using complete linkage method and a euclidean distance measure. (B) The boxplot compares nucleolar size values between normal-tumor tissue pairs, subdivided in two groups on the basis of the results of hierarchical clustering.

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