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Table 3 Mean serum concentration of alpha-1 antitrypsin in the phenotypes in both cohorts

From: Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls

Sample

Mean serum concentration of alpha-1 antitrypsin (mg/dl)

 

MM

MS

MZ

SS

SZ

General population

     

  N

256

60

9

1

1

  Mean

143.8

122.9

90.2

107.5

71.2

  SD

(20.5)

(30.6)

(10.7)

-

-

  Range

[88-235]

[75-202]

[75-107]

[107.5]

[71.2]

Colorectal cancer

     

  N

206

49

10

0

1

  Mean

208

167.7

139.2

-

124

  SD

(60)

(40.8)

(31.3)

-

-

  Range

[105-459]

[93-278]

[84-183]

-

[124]

P

0.0001

0.0001

0.001

NA

NA

  1. N number, SD standard deviation, NA not applicable. Significant differences found between MM, MS and MZ.