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Table 2 Correlations between the key metabolic-related proteins MCT4, PDK1 and CAIX expressions in CAFs and clinico-pathological data

From: A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer

  

MCT4

PDK1

CAIX

MCT1/MCT4*

Variable

n

%

p

%

p

%

p

%

p

PSA (ng/ml)

  

0.296

 

0.451

 

0.250

 

0.525

≤ 5.0

245

47.9

 

16.2

 

85.9

 

27.1

 

>5.0

123

44.0

 

17.5

 

82.2

 

27.5

 

pT

  

0.445

 

0.258

 

0.522

 

0.009

2

359

40.2

 

18.7

 

86.4

 

20.8

 

3

99

41.7

 

15.2

 

86.9

 

33.3

 

Perineural

         

Invasion

  

0.155

 

0.069

 

0.399

 

0.255

Absent

119

45.4

 

13.4

 

85.8

 

26.9

 

Present

327

39.4

 

19.8

 

87.2

 

23.3

 

Biochemical

         

Recurrence

  

0.104

 

0.176

 

0.003

 

0.052

Absent

410

40.2

 

18.5

 

75.4

 

22.6

 

Present

69

49.3

 

13.0

 

89.0

 

32.8

 
  1. The correlation between MCT1/MCT4 expression (*MCT1 expression in prostate tumour cells with concomitant expression of MCT4 in CAFs) and the clinico-pathological data is also presented.
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BMC Cancer

ISSN: 1471-2407

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