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Table 2 Correlations between the key metabolic-related proteins MCT4, PDK1 and CAIX expressions in CAFs and clinico-pathological data

From: A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer

   MCT4 PDK1 CAIX MCT1/MCT4*
Variable n % p % p % p % p
PSA (ng/ml)    0.296   0.451   0.250   0.525
≤ 5.0 245 47.9   16.2   85.9   27.1  
>5.0 123 44.0   17.5   82.2   27.5  
pT    0.445   0.258   0.522   0.009
2 359 40.2   18.7   86.4   20.8  
3 99 41.7   15.2   86.9   33.3  
Perineural          
Invasion    0.155   0.069   0.399   0.255
Absent 119 45.4   13.4   85.8   26.9  
Present 327 39.4   19.8   87.2   23.3  
Biochemical          
Recurrence    0.104   0.176   0.003   0.052
Absent 410 40.2   18.5   75.4   22.6  
Present 69 49.3   13.0   89.0   32.8  
  1. The correlation between MCT1/MCT4 expression (*MCT1 expression in prostate tumour cells with concomitant expression of MCT4 in CAFs) and the clinico-pathological data is also presented.