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Figure 5 | BMC Cancer

Figure 5

From: Antagonism of Sorafenib and Regorafenib actions by platelet factors in hepatocellular carcinoma cell lines

Figure 5

EGF and IGF counteract the inhibitory effect of Sorafenib. HepG2 cell line was cultured in 1% FBS medium in presence of different concentrations of serotonin, EGF and IGF-I or equivalent FBS (A) or incubated with the same doses of growth factors in presence of 1 μM Sorafenib (B). MTT assay was assessed after 48 h. The results are expressed as mean ± SD. *p < 0.05; **p < 0.001; ***p < 0.0001.

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