Figure 3From: Antagonism of Sorafenib and Regorafenib actions by platelet factors in hepatocellular carcinoma cell lines Platelet antagonism of drug-mediated inhibition of migration and invasion. Hep3B cell line was cultured in 1% FBS medium in presence of different platelets concentrations or FBS and incubated with 2.5-5 μM Sorafenib (A, C) or Regorafenib (B, C). Results of cell migration (A, B) and invasion (C) were expressed as percentage of migration (100% representing the completely closed wound) and fold increase over control invading cell, respectively.Back to article page