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Figure 6 | BMC Cancer

Figure 6

From: Immunotherapy of hepatocellular carcinoma with small double-stranded RNA

Figure 6

Treatment of HCC G-29-bearing mice with isRNA reduces the metastases area in different organs of mice. The ratio of the total metastases area to the total area of the organ was determined by microscopic analysis of organs sections, prepared at day 22. The data represent means ± SEM from five microscopic fields. Statistically significant differences between experimental groups and untreated group (control) are indicated by asterisks. **, P < 0.01; *, P < 0.05. Statistically significant differences between experimental groups and Lipofectamine-treated group (Mock) are indicated by triangles. ▲▲, P < 0.01; ▲, P < 0.05; Mann–Whitney U test. The area of metastases in the heart was evaluated using the average length of metastases and the mean number of metastases per mm2 as described in the Methods section.

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