| Crude HRa | Adjusted HR (FACT-C domain)a | Adjusted HR (SF-12 domain)a | Adjusted HR (SF-6D)a | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Estimate | 95% CI | P-value | Estimate | 95% CI | P-value | Estimate | 95% CI | P-value | Estimate | 95% CI | P-value |
Primary Tumour Site (Colon) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Rectum | 1.213 | (0.438,3.361) | 0.710 | 1.033 | (0.233,4.589) | 0.966 | 0.561 | (0.054,5.855) | 0.629 | 0.720 | (0.212,2.454) | 0.600 |
Active CRC Treatment (No) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Yes | 1.633 | (0.569,4.682) | 0.362 | 1.039 | (0.195,5.529) | 0.964 | 0.424 | (0.052,3.432) | 0.421 | 1.007 | (0.239,4.243) | 0.993 |
Stoma (Present) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Absent | 0.812 | (0.181,3.644) | 0.785 | 1.714 | (0.212,13.840) | 0.613 | 0.046 | (0.000,4.874) | 0.195 | 1.165 | (0.189,7.168) | 0.869 |
Time Since Diagnosis, months | 0.993 | (0.974,1.011) | 0.427 | 0.998 | (0.976,1.020) | 0.839 | 1.015 | (0.992,1.040) | 0.199 | 1.003 | (0.983,1.023) | 0.801 |
AJCC (Stage III) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  Stage IV | 1.898 | (0.688,5.242) | 0.216 | 1.928 | (0.365,10.193) | 0.440 | 2.791 | (0.319,24.446) | 0.354 | 1.659 | (0.371,7.411) | 0.508 |
FACT-C | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  PWB | 0.966 | (0.862,1.083) | 0.557 | 1.076 | (0.857,1.352) | 0.527 |  |  |  |  |  |  |
  SWB | 0.908 | (0.820,1.006) | 0.066 | 1.011 | (0.870,1.174) | 0.889 |  |  |  |  |  |  |
  EWB | 0.965 | (0.825,1.129) | 0.657 | 0.929 | (0.683,1.264) | 0.639 |  |  |  |  |  |  |
  FWB | 0.905 | (0.819,1.001) | 0.053 | 0.902 | (0.722,1.128) | 0.365 |  |  |  |  |  |  |
  CCS | 1.008 | (0.862,1.179) | 0.921 | 0.996 | (0.796,1.247) | 0.972 |  |  |  |  |  |  |
SF-12 | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  PF | 0.975 | (0.960,0.991) | 0.003b |  |  |  | 0.917 | (0.852,0.986) | 0.019b |  |  |  |
  RP | 0.975 | (0.956,0.994) | 0.009b |  |  |  | 0.996 | (0.944,1.051) | 0.882 |  |  |  |
  BP | 0.994 | (0.976,1.013) | 0.552 |  |  |  | 1.055 | (1.000,1.113) | 0.052 |  |  |  |
  GH | 0.970 | (0.948,0.992) | 0.008b |  |  |  | 0.846 | (0.746,0.958) | 0.009b |  |  |  |
  VT | 1.005 | (0.976,1.034) | 0.754 |  |  |  | 1.151 | (1.027,1.289) | 0.015b |  |  |  |
  SF | 0.987 | (0.972,1.003) | 0.109 |  |  |  | 1.015 | (0.970,1.063) | 0.523 |  |  |  |
  RE | 1.001 | (0.975,1.027) | 0.944 |  |  |  | 0.983 | (0.919,1.051) | 0.617 |  |  |  |
  MH | 1.016 | (0.975,1.058) | 0.457 |  |  |  | 1.128 | (1.005,1.265) | 0.040b |  |  |  |
SF-6D | 0.007 | (0.000,0.273) | 0.008b | Â | Â | Â | Â | Â | Â | 0.010 | (0.000,0.573) | 0.026b |
AIC | Â | Â | Â | 128.2 | 111.2 | 131.4 | ||||||
BIC | Â | Â | Â | 187.3 | 179.8 | 179.1 | ||||||
Harrell’s C-statistic |  |  |  | 0.824 (0.681,0.968) | 0.956 (0.909,1.002) | 0.799 (0.678,0.921) |