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Table 2 Univariate associations of clinical and pathologic features with recurrence for 871 patients with stage II colon cancer

From: Predictors of recurrence free survival for patients with stage II and III colon cancer

Patient/Tumor characteristics

Hazard ratio (95% CI)

P-value

Year of surgery (1-year increase)

0.97 (0.92 – 1.04)

0.38

Age at surgery (10-year increase)

0.91 (0.76 – 1.08)

0.26

Sex

  

  Female

1.0 (reference)

 

  Male

1.20 (0.79 – 1.83)

0.40

Adjuvant chemotherapy

  

  No

1.0 (reference)

 

  Yes

1.41 (0.87 – 2.27)

0.16

Tumor location

  

  Right

1.0 (reference)

 

  Sigmoid

1.37 (0.85 – 2.19)

0.20

  Transverse

0.69 (0.32 – 1.53)

0.37

  Left

0.58 (0.21 – 1.61)

0.30

Tumor location

  

  Right, transverse, or left

1.0 (reference)

 

  Sigmoid

1.50 (0.95 – 2.37)

0.08

Primary tumor size (20-mm increase)

0.96 (0.80 – 1.15)

0.66

Primary tumor classification

  

  T3

1.0 (reference)

 

  T4

3.17 (1.79 – 5.61)

<0.001

Total lymph nodes (10-node increase)

0.84 (0.65 – 1.07)

0.15

Tumor differentiation

  

  Well

1.0 (reference)

 

  Moderate

1.20 (0.76 – 1.89)

0.45

  Poor

1.07 (0.44 – 2.59)

0.88

Tumor differentiation

  

  Well or moderate

1.0 (reference)

 

  Poor

0.96 (0.42 – 2.20)

0.92

  1. Sample size for tumor size (N = 868), for total lymph nodes (N = 870), for adjuvant chemotherapy (N = 847) and for tumor differentiation (N = 869).