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Figure 1 | BMC Cancer

Figure 1

From: Indoleamine 2,3-dioxygenase (IDO) is frequently expressed in stromal cells of Hodgkin lymphoma and is associated with adverse clinical features: a retrospective cohort study

Figure 1

Representative features of immunohistochemistry in Hodgkin lymphoma (HL). (Inlet: an entire core tissue of tissue microarray) IDO (indoleamine 2,3-dioxygenase) is highly expressed in macrophages, dendritic cells, and some endothelial cells, but not in Hodgkin Reed Sternberg cells (HRS) or lymphocytes (A). CD68+ macrophages are found near HRS (B). CD163 is positive in both macrophages and some dendritic cells (C). CD4+ (D), CD8+ (E), or FOXP3+ (F) T-cells are found in the background of HL.

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