Table 3 Immunophenotype of “LP type” DLBCL (transformed from NLPHL) compared to conventional DLBCL
Staining pattern typically observed in DLBCL transformed from NLPHL | “LP type” DLBCL (n = 33) | Conventional DLBCL (n = 41) |
|---|---|---|
Bcl-6 strongly positive | 33 (100%) | 34 (83%) |
CD10 weakly or strongly positive | 12 (36%) | 15 (37%) |
CD75 weakly or strongly positive | 31 (94%) | 35 (85%) |
EMA weakly or strongly positive | 24 (73%)* | 11 (27%)* |
MUM1 weakly or strongly positive | 21 (63%) | 34 (83%) |
J-chain weakly or strongly positive | 24 (73%)* | 9 (22%)* |
Bcl2 weakly positive or negative | 20 (63%)* | 13 (32%)* |
CD21-positive follicular dendritic cells | 1/28 (4%) | 5/28 (18%) |
CD23-positive follicular dendritic cells | 0/28 (0%) | 5/28 (18%) |