Figure 1From: YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells YB-1 negatively regulates Sox2 protein expression in breast cancer cells. (A) Western blot of total YB-1 and Sox2 protein expression in MCF7 and ZR751 parental and (B) MCF7 and ZR751 RU, RR, and (C) Unsorted cells after 72-hour treatment of scrambled or YB-1 siRNA at 20 nM, denoted by siScr and siYB-1.Back to article page