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Table 3 Association between the level of HER2 and PathCR

From: Quantitative measurements of HER2 and phospho-HER2 expression: correlation with pathologic response to neoadjuvant chemotherapy and trastuzumab

A

 

no-PathCR

PathCR

 
 

N

Mean

SEM

N

Mean

SEM

P value

HER2 AQUA (base)

10

4766.3

1381.1

10

10214.6

639.1

0.0021

HER2 AQUA (post)

9

4853.5

1428.0

3

8309.3

1256.0

0.2191

Post/Base AQUA ratio

9

1.09

0.203

2

0.765

0.089

0.4897

B

 

no-Path CR

Path CR

 
 

N

Mean

SEM

N

Mean

SEM

P value

pHER2 AQUA (base)

10

2183.7

472.2

11

2604.9

538.7

0.5669

pHER2 AQUA (post)

9

2482.7

507.2

7

3042.4

1005.5

0.6030

Post/Base AQUA ratio

9

1.49

0.326

6

0.919

0.145

0.1953