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Table 1 Clinicopathological features for OSCC patients in Cohorts I-III

From: Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma

 

Cohort I† (n = 168)

Cohort II‡ (n = 198)

Cohort III* (n = 43)

Age (y)

   

19-39

13 (8%)

11 (6%)

2 (5%)

40-49

29 (17%)

24 (12%)

4 (9%)

50-59

43 (26%)

50 (25%)

12 (28%)

60-88

83 (49%)

113 (57%)

25 (58%)

Not available

0 (0%)

0 (0%)

0 (0%)

Sex

   

Female

47 (28%)

68 (34%)

20 (47%)

Male

121 (72%)

130 (66%)

23 (53%)

Not available

0 (0%)

0 (0%)

0 (0%)

Tumor site

   

Oral cavity

71 (42%)

198 (100%)

43 (100%)

Not available

97 (58%)

0 (0%)

0 (0%)

Cervical lymph node status

   

pN0

0 (0%)

70 (35%)

27 (63%)

pN1

0 (0%)

98 (50%)

16 (37%)

Not available

168 (100%)

30 (15%)

0 (0%)

Tumor size

   

T1-T2

30 (18%)

83 (42%)

36 (84%)

T3-T4

41 (24%)

111 (56%)

7 (16%)

Not available

97 (58%)

4 (2%)

0 (0%)

Clinical stage

   

I/II

71 (42%)

61 (31%)

25 (58%)

III/IV

97 (58%)

133 (67%)

18 (42%)

Not available

0 (0%)

4 (2%)

0 (0%)

Differentiation

   

Well

0 (0%)

30 (15%)

12 (30%)

Moderate

0 (0%)

128 (65%)

22 (51%)

Poor

0 (0%)

38 (19%)

7 (16%)

Not available

168 (100%)

2 (1%)

0 (0%)

Tumor inflammatory infiltration

   

Minimal

0 (0%)

0 (0%)

13 (30%)

Moderate

0 (0%)

0 (0%)

13 (30%)

Strong

0 (0%)

0 (0%)

16 (37%)

Not available

168 (100%)

198 (100%)

0 (0%)

Tobacco smoking history

   

Never smoker

15 (9%)

46 (23%)

18 (42%)

Former smoker

28 (17%)

87 (44%)

5 (12%)

Current smoker

28 (17%)

57 (29%)

12 (28%)

Chewing tobacco

0 (0%)

0 (0%)

1 (2%)

Not available

97 (58%)

8 (4%)

7 (16%)

p16

   

Negative

97 (58%)

0 (0%)

35 (81%)

Positive

0 (0%)

0 (0%)

8 (19%)

Not available

71 (42%)

198 (100%)

0 (0%)

  1. †Gene Expression Omnibus (GEO) accession numbers GSE41613 and GSE42743.
  2. ‡HNSC The Cancer Genome Atlas (TCGA) data.
  3. *FFPE samples from Sahlgrenska University Hospital, Gothenburg, Sweden.