Figure 5
From: RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer
RNPC1a regulated p53, p21, E-cadherin and vimentin in breast cancer cell. (A) RNPC1a positively regulated p21, while there was no significantly correlation was found between RNPC1a and wtp53 in MCF-7 cells. (B) RNPC1a positively regulated p21, while negatively regulated mutp53 in MDA-MB-231 cells. (C) RNPC1a positively regulated E-cadherin, while negatively regulated Vimentin in MDA-MB-231 cells. (D) RNPC1a positively regulated of E-cadherin, while there was no significantly correlation was found between RNPC1a and Vimentin in MCF-7 cells. The fold change of RNPC1a is shown below each lane. Arbitrarily set at 1.0 in control cells. The intensity of the bands was determined using densitometric analysis.