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Figure 11 | BMC Cancer

Figure 11

From: Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

Figure 11

Expression of P-JAK2, T-JAK2, P-STAT3 and T-STAT3 in mouse tumors generated from ip transplantation of control, paclitaxel, CYT387 and combination of paclitaxel plus CYT387- treated HEY cells. (A) Immunohistochemistry staining of tumor sections for the expression of P-JAK2 and T-JAK2 was performed as described in Materials. Quantification of staining was obtained as described in Materials by using three independent xenografts. Significant variations between the groups are indicated by **P<0.01. (B) Tumor sections were stained for P-STAT3 and T-STAT3 and quantification of the data was obtained as described in Figure 11 A. Significant variations between the groups are indicated by **P<0.01. Magnification 200×, scale bar = 10 μm

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