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Table 4 NIS expression in extrathyroidal cancer tissues

From: Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer

Primary cancer No of specimens NIS mRNA NIS protein positive (%) References
Bladder 24 n.d. 42 [13]
Cervix 11 n.d. 100 [13]
Colon 75 n.d. 63 [13]
Esophagus 15 n.d. 47 [13]
  20 n.d. 20 [13]
Liver 26 + 8 [74]
  20* + 100 [74]
Lung 58 n.d. 66 [13]
Ovary 37 n.d. 73 [13]
Pancreas 11 n.d. 64 [13]
Prostate 34 n.d. 74 [13]
Skin squamous 18 n.d. 56 [13]
Stomach 27 n.d. 59 [13]
  4 + n.d. [12]
Submandibular gland 3 + n.d. [12]
Testis 11 n.d. 9 [13]
  107 + 64 [75]
Uterus endometrium 25 n.d. 56 [13]
Metastatic cancer     
Liver** 15 n.d. 80 [76]
Brain*** 28 n.d. 84 [40]
  1. n.d.: not determined; *cholangiocarcinoma; **metastasis from breast, pancreas, colorectal and biliary cancers; ***metastasis from breast cancer.