Figure 1From: Prevalence of TPMT and ITPA gene polymorphisms and effect on mercaptopurine dosage in Chilean children with acute lymphoblastic leukemia Erythrocyte TPMT activity in Chilean patients with ALL. TPMT enzyme activity from packed red blood cells (PRBC) in patients with a TPMT variant allele (WT/Mut; n = 6) compared to the activity identified in patients without the variant present (WT/WT; n = 7). The Wilcoxon rank sum test and 95% confidence interval for differences between median values were used to compare TPMT activities between subpopulations. P values ≤0.05 were considered statistically significant.Back to article page