Factor | Sub-group | Patients with breast carcinoma and diabetes without metformin (N = 125) | Patients with breast carcinoma and diabetes on metformin (N = 128) | Patients with breast carcinoma without diabetes (N = 320) | P1 | P2 |
---|---|---|---|---|---|---|
Breast surgical procedure | Quadrantectomy or lumpectomy | 48 | 59 | 157 | 0.21 | 0.13 |
Mastectomy | 77 | 69 | 163 | |||
Axillary surgical procedure | Sentinel node biopsy | 54 | 61 | 147 | 0.43 | 0.73 |
Lymphadenectomy | 71 | 67 | 173 | |||
Adjuvant chemotherapy | No | 94 | 87 | 196 | 0.20 | 0.02 |
Yes | 31 | 41 | 124 | |||
Adjuvant hormone therapy | No | 14 | 15 | 76 | 0.89 | 0.0001 |
Yes | 111 | 113 | 244 | |||
Adjuvant trastuzumab | No | 118 | 115 | 285 | 0.17 | 0.22 |
Yes | 7 | 13 | 35 | |||
Adjuvant radiotherapy | No | 60 | 52 | 135 | 0.23 | 0.44 |
Yes | 65 | 76 | 185 |