BMC Cancer

Table 4 Correlation of clinicopathologic characteristics with Sirt3 expression

From: Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection

		iSirt3			pSirt3
Characteristics		Low	High	P value	Low	High	P value
Gender	Male	124	166	0.649	219	71	0.632
	Female	24	28		41	11
Age (Years)	≤52	75	93	0.616	135	32	0.051
	>52	73	101		125	49
HBV infection	No	47	47	0.122	68	26	0.296
	Yes	101	147		192	55
Liver cirrhosis	No	132	172	0.877	231	72	0.991
	Yes	16	22		29	9
ALT (U/L)	≤75	127	176	0.157	229	73	0.613
	>75	21	18		31	8
AFP (ng/ml)	≤20	51	81	0.170	90	42	0.005
	>20	97	113		170	39
γ-GT (U/L)	≤54	63	100	0.100	120	43	0.275
	>54	85	94		140	38
Tumor size (cm)	≤5	95	134	0.342	174	55	0.870
	>5	53	60		86	26
Tumor number	1	132	166	0.322	229	68	0.333
	≥2	16	28		31	13
Tumor thrombi	No	103	146	0.244	188	61	0.595
	Yes	45	48		72	20
Encapsulation	Yes	72	111	0.115	190	64	0.368
	No	76	83		70	17
Differentiation	Well	109	146	0.735	136	47	0.285
	Poor	39	48		124	34
TNM stage	I	64	90	0.562	122	32	0.242
	II/III	84	104		138	49
BCLC stage	A	96	137	0.258	178	55	0.925
	B/C	52	57		82	26

Note: χ2 tests for all the analysis. AFP, alpha-fetoprotein; γ-GT, γ-glutamyl transferase ; OS, overall survival ; TTR, time to recurrence.

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