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Figure 3 | BMC Cancer

Figure 3

From: A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells

Figure 3

Loss of PAX8 inhibits anchorage-independent growth in soft agar and suppresses tumorigenesis in nude mice. (A) soft agar growth of SKOVCtrl-, and siPAX8 cells was assessed and photographed. Columns, mean of three independent experiments; bars, SD (Ρ < 0.05). (B) growth curves of tumors in tumor-bearing nude mice injected with SKOV3, SKOVCtrl-, siCl32 and siCl48 cells. Data are plotted as the mean volume ± SD (n = 6 for each group). (C) representative images of SKOV3, SKOVCtrl-, siCl32 and siCl48 tumors following surgical resection.

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