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Table 1 CCR7 expression and clinicopathological characteristics of 105 consecutive patients and exclusively pT1 patients

From: CC-Chemokine receptor CCR7: a key molecule for lymph node metastasis in esophageal squamous cell carcinoma

  All patients (n = 105) (%) pT1 patients (n = 61) (%)
  CCR7(+) CCR7(-) p CCR7(+) CCR7(-) p
n = 28 (27) n = 77 (73)   n = 17 (28) n = 44 (72)
Age (mean ± SD) 62.3 ± 8.5 59.2 ± 7.2 0.070c 59.9 ± 7.4 60.0 ± 7.6 0.995c
Gender       
Male 26 70 1.000a 15 39 1.000a
Female 2 7 2 5
Histological grade       
1/2 26 69 1.000a 13 41 0.087a
3 2 8 4 3
Pathological T       
T1/T2 16 41 0.894b T1a 1 12 0.088a
T3/T4a 12 36 T1b 16 32
Pathological N       
Negative 5 32 0.037a 6 30 0.040b
Positive 23 45 11 14
UICC/AJCC stage       
I/II 11 41 0.296b 14 31 0.519a
III 17 36 3 13
Lymphatic invasion       
Absent 2 16 0.144a 4 24 0.044a
Present 26 61 13 20
Vessel invasion       
Absent 10 44 0.085b 10 38 0.045b
Present 18 33 7 6
  1. SD: standard deviation.
  2. a: Fisher’s exact probability test, b: Pearson’s χ-square test, c: Student’s t-test.