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Table 3 Cell death biological function category showing a significant fold change in genes belonging to HPMCs exposed to malignant ascites compared to benign fluids (Fold change > 2, P< 0.05)

From: Role of malignant ascites on human mesothelial cells and their gene expression profiles

Symbol Description Fold change
BDKRB1 Bradykinin receptor B1 -2.18
IL-8 Interleukin 8 -3.38
SOX17 SRY-box 17 -3.33
BMP2 Bone morphogenetic protein 2 -2.58
NR4A3 Nuclear receptor subfamily 4, group A, member 3 -2.30
RASD1 RAS, dexamethasone-induced 1 -2.27
PHLDA1 Pleckstrin homology-like domain, member 1 -3.40
TRIB3 Tribbles homolog 3 -2.22
HBEGF Heparin-binding EFG-like growth factor -2.20
SPRY2 Sprouty homolog 2 -2.03
AREG Amphiregulin 3.52
DDX58 DEAD box polypeptide 58 2.37
DEPDC1 DEP domain containing 1 7.06
IRS2 Insulin receptor substrate 2 2.11
SMAD5 SMAD, family member 5 2.10
MT1A Metallothionein 1A 2.10
MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 2.04