Skip to main content
Figure 3 | BMC Cancer

Figure 3

From: Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

Figure 3

EGFR over expression induces tamoxifen and fulvestrant resistance. Parental MCF7 and MCF7-EGFR cells were estrogen starved 48 hours prior to a 5 day proliferation period in the presence of 0.1 nM E2 with a concentration series TAM (A) or fulvestrant (B), with or without 100 ng/mL EGF. Afterwards, cells were fixed with 50% TCA and stained with sulforhodamin B, which absorbance was measured at 540 nm. Graphs represent the average ± SEM of three independent experiments.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us