Figure 4
From: Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis
Correlation of Zalipsis IC50 with RTK activation. A) Graph showing the mean IC50 values for Zalypsis with respect to the average values for all IC50s. The bold bars indicate no constitutive activation of RTKs. The hatched bars indicate the activation of RTKs. The number above the bars shows the average IC50 values (nM) for the nine tumor cell lines. B) Graph comparing in groups the IC50 of cell lines with RTK activated or not activated. The Student T test was used to explore the statistical relevance.