Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover

Figure 4

Protein stability of GATA3 in cells treated with ERα agonist or antagonist. A) T47D and MCF7 cells were grown in hormone-depleted conditions and then treated, at Time 0, with 50 nM 17β-estradiol (E2) for 24 hours. B) Quantification of Western blot signal intensity in panel B. C) T47D and MCF7 cells were treated with 100 nM ICI 182,780 (ICI), an estrogen receptor antagonist, for 24 hours.

Back to article page