Table 3 Summary of univariate and multivariate Cox regression analysis of overall survival duration

Gender

    Male vs. female

0.583

1.176

0.660-2.097

0.930

1.027

0.560-1.885

Age

    ≥50vs. <50 years

0.352

1.281

0.760-2.159

0.933

0.977

0.568-1.680

Family tumor history

    Yes vs. No

0.970

1.022

0.319-3.273

0.917

0.940

0.289-3.052

Smoking

    Yes vs. No

0.979

1.010

0.495-2.060

0.452

1.340

0.625-2.876

Chemotherapy

    Yes vs. No

0.585

1.220

0.598-2.489

0.709

1.171

0.512-2.679

Radiotherapy

    Yes vs. No

0.002

0.308

0.145-0.654

0.009

0.280

0.108-0.727

T classification

    T₁-T₂ vs. T₃-T₄

0.000

2.611

1.533-4.446

N classification

    N₀-N1 vs. N_2--N₃

0.002

2.317

1.367-3.927

M classification

    M₀ vs. M₁

0.000

7.280

3.519-15.061

Clinical stage

    I-II vs. III-IV

0.000

5.222

2.467-11.054

0.000

4.527

2.041-10.042

Expression of CDK4

High expression vs. low expression

0.099

1.554

0.920-2.626

0.087

1.671

0.928-3.008