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Figure 5 | BMC Cancer

Figure 5

From: Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1

Figure 5

Triptolide time- and dose-dependently inhibited Mcl-1 protein expression and induced PARP cleavage in CCA cells. (A) Cells were treated with 100 nM triptolide for indicated times or (B) with indicated concentrations of triptolide for 12 h. Whole cell extracts were prepared and analyzed using indicated antibodies. β-actin served as a loading control. (C) HuCCT1 and QBC939 cells were treated with 100 nM triptolide for 24 h and then analyzed for the expression of Mcl-1 by immunofluorescence (original magnification, ×200).

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BMC Cancer

ISSN: 1471-2407

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