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Figure 2 | BMC Cancer

Figure 2

From: BIMELis a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine

Figure 2

BSO augments ATO-induced cell death via ROS-mediated mitochondrial injury. A, After treatment as Figure 1A, the release of cytochrome c and the cleavage of caspase 9 were determined by immunoblotting. B, MOMP with NIR dye and Hoechst staining was analyzed by confocal microscopy. Magnification ×40. The results are presented as % untreated cells with SD. A typical result of 3 independent experiments is shown.

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