Figure 1

Immunohistochemical stainings of colorectal cancer tissue sections with anti-uPAR and anti-cell marker antibodies. a) uPAR staining on TMA cores from tissue of colorectal cancer patients: I) Negative in neoplastic and stromal cells, II) positive in neoplastic and stromal cells, III) positive in neoplastic and negative for stromal cells and IV) negative in neoplastic and positive for stromal cells. b) Sequential stained sections showing expression of the urokinase receptor in comparison with various markers for tumor-associated stromal cells: I) with endothelial cells, II) with monocytes/macrophages, III) neoangiogenic cells and IV) with myofibroblasts. Bars in a) and b) indicate ~50 μm.