Table 3 Incidence of malignant and benign tumors induced by DMBA
| Wild-Type (N = 28) | MMTV-myr-Akt1 + (N = 28) | |||
|---|---|---|---|---|
| Virgin (N = 17) | Post-lactating (N = 11) | Virgin (N = 17) | Post-lactating (N = 11) | |
| Mammary carcinoma | 2 (11.8%) | 0 | 4 (23.5%) | 5 (45.5%) |
| Salivary gland carcinoma | 1 (5.9%) | 0 | 0 | 0 |
| Stomach carcinoma | 1 (5.9%) | 0 | 0 | 1 (9.1%) |
| Malignancy in lung | 1 (5.9%) | 0 | 0 | 0 |
| Benign mammary tumor | 0 | 0 | 2 (11.8%) | 1 (9.1) |
| Endometrial hyperplasia | 1 (5.9%) | 0 | 0 | 0 |
| Benign skin tumor | 1 (5.9%) | 0 | 0 | 1 (9.1) |