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Figure 1 | BMC Cancer

Figure 1

From: Combination of expression levels of miR-21 and miR-126 is associated with cancer-specific survival in clear-cell renal cell carcinoma

Figure 1

Expression of miR-126 and miR-21 in RCC. Box-Whisker-Plot : A) Relative expression of miR-21 and miR-126 in RCC and normal renal tissue (nā€‰=ā€‰103). MiR-21 expression is significantly higher in RCC (pā€‰<ā€‰0,001), but overall miR-126 expression is not changed (pā€‰=ā€‰0.57) in RCC compared to the expression of control tissue. Expression was analysed by qRT-PCR and normalized against RNU6b. P-values were calculated by unpaired students t-test. B) Proportion of RCC patients with dysregulation of miR-21 and miR-126: Expression of miRs in tumour and control tissue was verified by qRT-PCR in triplicates. MiR expression ratio of each tumour specimen compared to the expression in corresponding adjacent normal tissue was calculated by the Ī”Ī”Ct method. All patients were divided into three groups byā€‰>ā€‰< 2 fold up- or down-regulation of miR-21 or miR-126 in RCC.

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