Table 3 The top significant molecular and cellular functions identified by IPA
Molecular and cellular functions | p value | No. genes |
|---|---|---|
Cellular movement | 5.30E-08-1.22E-02 | 344 |
Cell cycle | 7.12E-07-1.22E-02 | 233 |
DNA replication, recombination and Rrepair | 7.12E-07-1.18E-02 | 124 |
Cellular development | 1.16E-06-1.22E-02 | 433 |
Cellular assembly and organization | 4.97E-06-1.22E-02 | 322 |
Canonical pathways | p value | Ratio |
Role of BRCA1 in DNA damage response | 1.86E-04 | 17/65 (0.262) |
Primary immunodeficiency signaling | 3.97E-03 | 11/62 (0.177) |
G protein signaling mediated by Tubby | 5.05E-03 | 9/42 (0.214) |
Aryl hydrocarbon Rreceptor signaling | 5.39E-03 | 25/161 (0.155) |
Regulation of actin-based motility by Rho | 7.5E-03 | 17/89 (0.191) |