Table 3 Assessments and instruments used

Components of MetS (5):

X

X

X

Biomarkers- Glucose, HDL, triglycerides

Analyzed in peripheral blood

X

X

X

Blood pressure

Pressure cuff under resting conditions

X

X

X

Waist circumference

Measuring tape

X

X

X

Secondary endpoints

Cardiorespiratory fitness

4-minute walk test

X

X

X

Muscle strength

10-RM- leg extension, leg flexion, chest press, seated row

X

X

X

Body composition

DEXA, weight, height, lean mass, % body fat, hip circumference

X

X

X

Quality of life

SF-36, FACT-B, CES-D

X

X

X

Shoulder strength

Muscle force for SE and ER

X

X

X

Shoulder ROM

Measured with goniometer at 90° ER, forward flexion,

X

X

X

Upper limb musculoskeletal disorder assessment

DASH, PSS

X

X

X

Biomarkers- inflammation & endocrine function

Analyzed in peripheral blood

X

X

X

Others

Breast cancer characteristics

Family history, TNM status, ER/PR status, HER-2 score

X

Medical history

Recording of any pre-existing disease and allergies

X

Treatment data

Pre-treatment: date and type of breast cancer, affected lymph nodes, chemotherapy type and dose, radiation- technique, type, dose, start/stop date, hormone therapy

X