Table 3 Association between FAK expression and prognostic factors (categorical variables)
FAK location | Parameter | Mean FAK score (95% CI) | p-value |
|---|---|---|---|
Vessels | Tumour grade | Â | Â |
| Â | 1 or 2 | 156.2 (124.6-187.8) | Â |
| Â | 3 | 200.2 (177.9-222.6) | 0.008 |
| Â | Lymph node involvement | Â | Â |
| Â | Yes | 184.7 (157.7-211.7) | Â |
| Â | No | 179.6 (152.8-206.5) | 0.765 |
| Â | ER status | Â | Â |
| Â | Positive | 161.3 (139.9-184.6) | Â |
| Â | Negative | 213.7 (184.7-242.7) | 0.005 |
| Â | PR status | Â | Â |
| Â | Positive | 156.8 (131.6-181.9) | Â |
| Â | Negative | 212.8 (186.7-238.9) | 0.002 |
| Â | Her2 status | Â | Â |
| Â | Positive | 215.8 (181.6-250.0) | Â |
| Â | Negative | 169.8 (148.0-191.6) | 0.022 |
| Â | Molecular sub-type | Â | Â |
| Â | Luminal A vs Non-Luminal A | 135.4 (107.6-163.2) vs 211.8 (189.0-234.6) | <0.001 |
| Â | Luminal B vs Non-Luminal B | 208.0 (169.1-246.9) vs 176.5 (155.5-196.6) | 0.130 |
| Â | Her2 positive vs Non-Her2 | 235.9 (155.8-316) vs 178.5 (159.5-197.4) | 0.121 |
| Â | TN versus Non-TN | 208.4 (176.6-240.1) vs 170.3 (147.6-193.0) | 0.043 |
Tumour cells | Tumour grade | Â | Â |
| Â | 1 or 2 | 4.1 (3.6-4.7) | Â |
| Â | 3 | 5.1 (4.8-5.5) | 0.001 |
| Â | Lymph node involvement | Â | Â |
| Â | Yes | 5.1 (4.7-5.4) | Â |
| Â | No | 4.5 (4.0-5.0) | 0.249 |
| Â | ER status | Â | Â |
| Â | Positive | 4.4 (4.0-4.9) | Â |
| Â | Negative | 5.2 (4.8-5.6) | 0.013 |
| Â | PR status | Â | Â |
| Â | Positive | 4.4 (4.0-4.9) | Â |
| Â | Negative | 5.1 (4.7-5.5) | 0.048 |
| Â | Her2 status | Â | Â |
| Â | Positive | 5.1 (4.6-5.6) | Â |
| Â | Negative | 4.6 (4.2-5.0) | 0.215 |
| Â | Molecular sub-type | Â | Â |
| Â | Luminal A vs Non-Luminal A | 4.1 (3.5-4.7) vs 5.2 (4.8-5.5) | 0.001 |
| Â | Luminal B vs Non-Luminal B | 5.0 (4.4-5.6) vs 4.7 (4.3-5.0) | 0.408 |
| Â | Her2 positive vs Non-Her2 | 5.3 (4.5-6.1) vs 4.7 (4.4-5.0) | 0.406 |
| Â | TN versus Non-TN | 5.2 (4.7-5.7) vs 4.5 (4.1-4.9) | 0.033 |