Table 4 Hematological, clinical and radiation toxicities per patient (NCI/CTC) (ITT population, n = 70)
Induction therapy (n =70), n (%) | Consolidation therapy (n = 49), n (%) | |||
|---|---|---|---|---|
All grades | Grade 3-4 | All grades | Grade 3-4 | |
Hematological toxicities per patient | ||||
Anemia | 36 (51.4) | - | 39 (79.6) | 2 (4.1) |
Neutropenia | 31 (44.3) | 17 (24.3) | 20 (40.8) | 1 (2) |
Leukopenia | 27 (38.6) | 6 (8.6) | 30 (61.2) | 1 (2) |
Thrombocytopenia | 15 (21.4) | - | 11 (22.4) | - |
Febrile neutropenia (Pizzo) | 2 (2.85) | - | ||
Clinical toxicities (NCI-CTC) | ||||
Fatigue | 31 (44.3) | 2 (2.9) | 23 (46.9) | - |
Nausea | 29 (41.4) | 1 (1.4) | 15 (30.6) | 1 (2) |
Vomiting | 18 (25.7) | 2 (2.9) | 10 (20.4) | 1 (2) |
Diarrhea | 11 (15.7) | - | 5 (10.2) | - |
Constipation | 9 (12.9) | - | 2 (4.1) | - |
Anorexia | 6 (8.6) | - | 3 (6.1) | 1 (2) |
Hypercreatininemia | 1 (1.4) | - | - | - |
Radiation toxicities | ||||
Esophagitis | - | - | 13 (26.5) | - |
Skin injury | - | - | 12 (24.5) | - |
Dysphagia | - | - | 6 (12.2) | - |
Pain | - | - | 3 (6.1) | |
Pulmonary radiation injury | - | - | 1 (2) | 1 (2) |
Radiation mucositis | - | - | 1 (2) | - |
Pneumonitis | - | - | 1 (2) | - |