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Table 4 Densitometry analysis of the SDF-1 expression on the bones of the representative images from Figure 4 D i-v

From: Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches

 

IntDen

StdDev

%Area

Secondary negative control

1040.48*

24.75

0.69

Balb/C with no tumor

1105.238*

26.41

1.15

SKG with no tumor

1432.77*

22.72

1.29

SKG + BC + IgG

2124.35

26.42

10.25

SKG + BC + anti-IL-17A

1250.82*

22.09

2.72

  1. (i) Secondary antibody only; (ii) Balb/C with no tumor and no AA; (iii) SKG with no tumor; (iv) 4 T1 tumor bearing SKG mice treated with control IgG antibody or with anti-IL-17A antibody (v). (*P < 0.05: all groups against SKG + BC + IgG).