Skip to main content

Advertisement

Table 4 Densitometry analysis of the SDF-1 expression on the bones of the representative images from Figure 4 D i-v

From: Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches

  IntDen StdDev %Area
Secondary negative control 1040.48* 24.75 0.69
Balb/C with no tumor 1105.238* 26.41 1.15
SKG with no tumor 1432.77* 22.72 1.29
SKG + BC + IgG 2124.35 26.42 10.25
SKG + BC + anti-IL-17A 1250.82* 22.09 2.72
  1. (i) Secondary antibody only; (ii) Balb/C with no tumor and no AA; (iii) SKG with no tumor; (iv) 4 T1 tumor bearing SKG mice treated with control IgG antibody or with anti-IL-17A antibody (v). (*P < 0.05: all groups against SKG + BC + IgG).