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Table 3 Densitometry analysis of the SDF-1 expression on the lungs of the representative images from Figure 4 Ci-v

From: Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches

 

IntDen

StdDev

%Area

Secondary negative control

32.97**

30.27

0.3

Balb/C with no tumor

1001.25*

26.59

1.23

SKG with no tumor

1154.60*

25.53

1.98

SKG + BC + IgG

4249.27

21.13

25.49

SKG + BC + anti-IL-17A

1179.99*

24.97

4.49

  1. (i) Secondary antibody only; (ii) Balb/C with no tumor and no AA; (iii) SKG with no tumor; (iv) 4 T1 tumor bearing SKG mice treated with control IgG antibody or with anti-IL-17A antibody (v) (*P < 0.05: Balb/C, SKG, SKG + BC + anti-IL-17A against SKG + BC + IgG; **P < 0.01: Secondary antibody against all other groups).