Table 2 Correlation between clinicopathological characteristics and Lgr5 expression in patients with SCCE
From: Primary small cell carcinoma of the esophagus: clinicopathological study of 44 cases
| Lgr5 expression | |||
|---|---|---|---|
| Characteristics | Low or none No. cases | High No. cases | Chi-square test P-value |
| Gender | .601 | ||
| male | 18 | 15 | |
| female | 5 | 6 | |
| Age | .241 | ||
| >60 | 6 | 9 | |
| <=60 | 17 | 12 | |
| Tumor length(39 available) | .256 | ||
| > = 5 cm | 9 | 12 | |
| <5 cm | 11 | 7 | |
| Tumor location | .721 | ||
| Upper thoracic segment | 3 | 4 | |
| Middle thoracic segment | 11 | 11 | |
| Lower thoracic segment | 9 | 6 | |
| AJCC stage(43 available) | .003 | ||
| I/II | 15 | 4 | |
| III/IV | 8 | 16 | |
| T classification(40 available) | .206 | ||
| T < =2 | 12 | 8 | |
| T > 2 | 8 | 12 | |
| N classification(42 available) | .003 | ||
| N0 | 13 | 3 | |
| N+ | 9 | 17 | |
| M classification(43 available) | .329 | ||
| M0 | 19 | 14 | |
| M1 | 4 | 6 | |
| Chemotherapy response(19 available) | .013 | ||
| Reached CR/PR | 5 | 1 | |
| Did not reach CR/PR | 3 | 10 | |