Table 2 Correlation between klotho expression and clinicopathological features of gastric cancer

Sex

0.035

0.851

  Male

75

44 (58.7%)

31

  Female

28

17 (60.7%)

11

Tumor diameter

3.464

0.063

  <5 cm

74

48 (64.9%)

26

  ≥5 cm

29

13 (44.8%)

16

Lauren classification

1.375

0.241

  Diffuse type

61

39 (63.9%)

22

  Intestinal type

42

22 (52.4%)

20

Differentiation

0.203

1.000

  Well

3

2 (66.7%)

1

  Moderate

27

16 (59.3%)

11

  Poor or no

73

43 (58.9%)

30

Histology classification

3.220

0.347

  Papillary adenocarcinoma

1

0 (0.0%)

6

  Tubular adenocarcinoma

83

48 (57.8%)

48

  Mucinous adenocarcinoma

9

5 (55.6%)

32

  Signet-ring cell carcinoma

10

8 (80.0%)

4

Lymph node metastasis

7.058

0.008

  Yes

60

29 (48.3%)

31

  No

43

32 (74.4%)

11

Distant metastasis

4.778

0.040

  Yes

6

1 (16.7%)

5

  No

97

60 (61.9%)

37

TNM stage

16.763

0.001

  I

24

22 (91.7%)

2

  II

30

18 (60.0%)

12

  III

39

18 (46.2%)

21

  IV

10

3 (30.0%)

7