Figure 3

Prognostic impact of the combination status of NS and p53 in the patients with primary breast cancer. A. Disease-free survival (DFS) curves for the 77 patients with p53-positive tumors and for the 143 patients with p53-negative tumors. These two curves differ significantly (P = 0.006). B. This figure shows three disease-free survival (DFS) curves: for the 57 patients with NS-positive and p53-positive tumors (‘unfavorable group’), for 105 patients comprising 20 NS-negative and p53-positive tumors and 85 NS-positive and p53-negative tumors (‘intermediate’ group), and for 58 patients with NS-negative and p53-negative tumors (‘favorable’ group). The unfavorable group has significantly shorter DFS time than the intermediate group or the favorable group (log-rank test P = 0.034 and P = 0.0007, respectively).