Skip to main content

Table 2 Assessment of univariate performance of individual gene signatures on Distant Metastasis Free Survival prediction

From: Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status

  Ca(95% CI) PVEb(%)
Intrinsic-RORs 0.598 [0.58, 0.62] 1.60
PAM50-RORs 0.658 [0.64, 0.68] 5.74
70-gene 0.612 [0.60, 0.63] 2.76
76-gene 0.642 [0.62, 0.66] 4.58
GGI 0.656 [0.64, 0.67] 4.87
WR 0.651 [0.63, 0.67] 4.83
Hypoxia 0.525 [0.50, 0.55] 0.60
RS 0.648 [0.63, 0.67] 4.05
EP 0.648 [0.63, 0.67] 4.78
  1. aC: concordance index.
  2. b PVE: proportion of variation explained in the outcome variable, comparable with the R 2 in regression modeling.
  3. The variability of the C-index was estimated from 1000 bootstrap iterations.