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Table 2 Assessment of univariate performance of individual gene signatures on Distant Metastasis Free Survival prediction

From: Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status

 

Ca(95% CI)

PVEb(%)

Intrinsic-RORs

0.598 [0.58, 0.62]

1.60

PAM50-RORs

0.658 [0.64, 0.68]

5.74

70-gene

0.612 [0.60, 0.63]

2.76

76-gene

0.642 [0.62, 0.66]

4.58

GGI

0.656 [0.64, 0.67]

4.87

WR

0.651 [0.63, 0.67]

4.83

Hypoxia

0.525 [0.50, 0.55]

0.60

RS

0.648 [0.63, 0.67]

4.05

EP

0.648 [0.63, 0.67]

4.78

  1. aC: concordance index.
  2. b PVE: proportion of variation explained in the outcome variable, comparable with the R 2 in regression modeling.
  3. The variability of the C-index was estimated from 1000 bootstrap iterations.
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BMC Cancer

ISSN: 1471-2407

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