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Table 5 Odds ratios (OR) and 95% confidence intervals (CI) of subsequent cancer by cancer site for cohorts with a primary cutaneous malignant melanoma (CMM) or cutaneous squamous cell carcinoma (SCC) relative to that of the general population, adjusted for covariates shown in Table 21

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

   CMM SCC
ICD-10 Cancer site2 Events3 OR (95% CI) Events OR (95% CI)
C00-144 Oral cavity 2768 0.96 (0.68,1.34) 2876 2.70 (2.19,3.34)
C07-08 Salivary glands 257 0.62 (0.14,2.74) 291 8.89 (5.29,14.93)
C18 Colon 13 281 1.28 (1.12,1.46) 13 190 1.62 (1.43,1.82)
C19-21 Rectum 6696 1.15 (0.93,1.42) 6768 1.10 (0.91,1.33)
C25 Pancreas 4551 1.14 (0.89,1.45) 4590 1.56 (1.27,1.91)
C33,34,38 Lung 12 347 0.72 (0.62,0.84) 12 613 1.23 (1.09,1.36)
C50 Breast 17 275 1.21 (1.07,1.36) 16 956 1.16 (1.01,1.34)
C50-58 Female organs 29 775 1.11 (1.02,1.22) 29 349 1.08 (0.96,1.21)
C61 Prostate 17 398 1.17 (1.02,1.34) 17 797 1.28 (1.14,1.43)
C64-68 Urinary organs 10 607 1.00 (0.85,1.18) 10 787 1.18 (1.03,1.37)
C70-72 CNS5 4348 1.73 (1.39,2.15) 4149 1.07 (0.79,1.44)
C73 Thyroid 1437 1.75 (1.19,2.56) 1435 1.27 (0.75,2.16)
C81-85 Lymphoma 4672 1.42 (1.14,1.76) 4678 2.78 (2.33,3.32)
C91-95 Leukemia 6096 1.63 (1.33,1.99) 6162 2.15 (1.83,2.53)
C00-966 Other sites 21 969 1.27 (1.13,1.43) 22 373 1.67 (1.51,1.84)
C43 CMM 6363 7.99 (7.19,8.88) 5827 3.45 (2.94,4.05)
C44 SCC 5382 3.31 (2.86,3.82) 6906 14.4 (13.2,15.7)
C00-96 All sites 147 974 1.53 (1.48,1.59) 149 791 2.30 (2.22,2.37)
C00-967 All, exc. skin 136 229 1.16 (1.11,1.21) 137 058 1.51 (1.46,1.57)
  1. 1The number of cancer cases in the SIR-analyses differs slightly from that used in the logistic regression analyses as the data were extracted on different dates from the Cancer Registry of Norway. The number of cases are nevertheless quite similar (CMM: SIR 28 156 vs 28 069, events 4009 vs 3996 and SCC: SIR 24 713 vs 24 620, event 5623 vs 5612). 2The cancer sites are mutually exclusive. 3Observed number of events in a 20% general population sample and the cohort of skin cancer survivors. 4Includes ICD-10 codes C00-06 and C09-14. 5Central nervous system tumors. 6Includes ICD-10 codes 150–152, 155, 156, 158–161, 164, 178, 179, 192, and 195–199. 7All sites except C43 and C44.