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Table 5 Odds ratios (OR) and 95% confidence intervals (CI) of subsequent cancer by cancer site for cohorts with a primary cutaneous malignant melanoma (CMM) or cutaneous squamous cell carcinoma (SCC) relative to that of the general population, adjusted for covariates shown in Table 21

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

  

CMM

SCC

ICD-10

Cancer site2

Events3

OR (95% CI)

Events

OR (95% CI)

C00-144

Oral cavity

2768

0.96 (0.68,1.34)

2876

2.70 (2.19,3.34)

C07-08

Salivary glands

257

0.62 (0.14,2.74)

291

8.89 (5.29,14.93)

C18

Colon

13 281

1.28 (1.12,1.46)

13 190

1.62 (1.43,1.82)

C19-21

Rectum

6696

1.15 (0.93,1.42)

6768

1.10 (0.91,1.33)

C25

Pancreas

4551

1.14 (0.89,1.45)

4590

1.56 (1.27,1.91)

C33,34,38

Lung

12 347

0.72 (0.62,0.84)

12 613

1.23 (1.09,1.36)

C50

Breast

17 275

1.21 (1.07,1.36)

16 956

1.16 (1.01,1.34)

C50-58

Female organs

29 775

1.11 (1.02,1.22)

29 349

1.08 (0.96,1.21)

C61

Prostate

17 398

1.17 (1.02,1.34)

17 797

1.28 (1.14,1.43)

C64-68

Urinary organs

10 607

1.00 (0.85,1.18)

10 787

1.18 (1.03,1.37)

C70-72

CNS5

4348

1.73 (1.39,2.15)

4149

1.07 (0.79,1.44)

C73

Thyroid

1437

1.75 (1.19,2.56)

1435

1.27 (0.75,2.16)

C81-85

Lymphoma

4672

1.42 (1.14,1.76)

4678

2.78 (2.33,3.32)

C91-95

Leukemia

6096

1.63 (1.33,1.99)

6162

2.15 (1.83,2.53)

C00-966

Other sites

21 969

1.27 (1.13,1.43)

22 373

1.67 (1.51,1.84)

C43

CMM

6363

7.99 (7.19,8.88)

5827

3.45 (2.94,4.05)

C44

SCC

5382

3.31 (2.86,3.82)

6906

14.4 (13.2,15.7)

C00-96

All sites

147 974

1.53 (1.48,1.59)

149 791

2.30 (2.22,2.37)

C00-967

All, exc. skin

136 229

1.16 (1.11,1.21)

137 058

1.51 (1.46,1.57)

  1. 1The number of cancer cases in the SIR-analyses differs slightly from that used in the logistic regression analyses as the data were extracted on different dates from the Cancer Registry of Norway. The number of cases are nevertheless quite similar (CMM: SIR 28 156 vs 28 069, events 4009 vs 3996 and SCC: SIR 24 713 vs 24 620, event 5623 vs 5612). 2The cancer sites are mutually exclusive. 3Observed number of events in a 20% general population sample and the cohort of skin cancer survivors. 4Includes ICD-10 codes C00-06 and C09-14. 5Central nervous system tumors. 6Includes ICD-10 codes 150–152, 155, 156, 158–161, 164, 178, 179, 192, and 195–199. 7All sites except C43 and C44.
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BMC Cancer

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