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Table 4 Standard incidence ratios (SIR) and 95% confidence intervals (CI) for a second malignancy by cancer site in men and women with a history of cutaneous squamous cell carcinoma (SCC), adjusted for age and calendar period

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

  

Women (N = 10 9651)

Men (N = 13 7481)

ICD-10

Cancer site2

O3

SIR (95% CI)

O3

SIR (95% CI)

C00-144

Mouth, pharynx

38

3.03 (2.20,4.16)

114

3.23 (2.69,3.87)

C07-08

Salivary glands

11

6.69 (3.71,12.1)

17

6.19 (3.85,9.95)

C18

Colon

176

1.25 (1.08,1.45)

197

1.09 (0.95,1.25)

C19-21

Rectum

45

0.86 (0.64,1.14)

96

0.98 (0.80,1.20)

C25

Pancreas

45

1.03 (0.77,1.38)

82

1.39 (1.12,1.73)

C33,34,38

Lung

82

1.46 (1.17,1.81)

303

1.49 (1.32,1.66)

C50

Breast

204

1.15 (1.00,1.32)

-

-

C50-58

Female organs

320

1.11 (0.99,1.24)

-

-

C61

Prostate

-

-

650

1.14 (1.06,1.23)

C64-68

Urinary organs

42

0.69 (0.51,0.94)

222

1.08 (0.94,1.23)

C70-72

CNS5

17

0.65 (0.40,1.04)

32

1.10 (0.78,1.56)

C73

Thyroid

12

7.30 (4.15,12.8)

3

0.60 (0.19,1.85)

C81-85

Lymphoma

64

2.14 (1.67,2.74)

113

2.41 (2.00,2.90)

C91-95

Leukemia

65

1.33 (1.04,1.69)

150

1.70 (1.45,1.99)

C00-966

Other sites

183

1.13 (0.98,1.31)

371

1.37 (1.23,1.51)

C43

CMM

95

3.09 (2.52,3.78)

122

2.76 (2.31,3.29)

C44

SCC

715

9.88 (9.18,10,6)

1249

10.1 (9.51,10.6)

C00-96

All sites

1898

1.89 (1.81,1.98)

3725

1.91 (1.84,1.96)

C00-967

All, exc. skin

1088

1.22 (1.15,1.30)

2354

1.33 (1.28,1.39)

C00-968

All, exc. SCC

1183

1.23 (1.16,1.30)

2476

1.31 (1.25,1.36)

  1. 1The number of cancer cases in the SIR-analyses differs slightly from that used in the logistic regression analyses as the data were extracted on different dates from the Cancer Registry of Norway. 2The cancer sites are not mutually exclusive. 3Observed number of cases. 4Includes ICD-10 codes C00-06 and C09-14. 5Central nervous system tumors. 6Includes ICD-10 codes C15-17, C22-24, C26, C30-32, C37, C39-41, C45-49, C60, C62-63, C69, C74-76, C80, C88, C90. 7All sites except C43 and C44. 8All sites except C44.