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Table 4 Standard incidence ratios (SIR) and 95% confidence intervals (CI) for a second malignancy by cancer site in men and women with a history of cutaneous squamous cell carcinoma (SCC), adjusted for age and calendar period

From: New malignancies after squamous cell carcinoma and melanomas: a population-based study from Norway

   Women (N = 10 9651) Men (N = 13 7481)
ICD-10 Cancer site2 O3 SIR (95% CI) O3 SIR (95% CI)
C00-144 Mouth, pharynx 38 3.03 (2.20,4.16) 114 3.23 (2.69,3.87)
C07-08 Salivary glands 11 6.69 (3.71,12.1) 17 6.19 (3.85,9.95)
C18 Colon 176 1.25 (1.08,1.45) 197 1.09 (0.95,1.25)
C19-21 Rectum 45 0.86 (0.64,1.14) 96 0.98 (0.80,1.20)
C25 Pancreas 45 1.03 (0.77,1.38) 82 1.39 (1.12,1.73)
C33,34,38 Lung 82 1.46 (1.17,1.81) 303 1.49 (1.32,1.66)
C50 Breast 204 1.15 (1.00,1.32) - -
C50-58 Female organs 320 1.11 (0.99,1.24) - -
C61 Prostate - - 650 1.14 (1.06,1.23)
C64-68 Urinary organs 42 0.69 (0.51,0.94) 222 1.08 (0.94,1.23)
C70-72 CNS5 17 0.65 (0.40,1.04) 32 1.10 (0.78,1.56)
C73 Thyroid 12 7.30 (4.15,12.8) 3 0.60 (0.19,1.85)
C81-85 Lymphoma 64 2.14 (1.67,2.74) 113 2.41 (2.00,2.90)
C91-95 Leukemia 65 1.33 (1.04,1.69) 150 1.70 (1.45,1.99)
C00-966 Other sites 183 1.13 (0.98,1.31) 371 1.37 (1.23,1.51)
C43 CMM 95 3.09 (2.52,3.78) 122 2.76 (2.31,3.29)
C44 SCC 715 9.88 (9.18,10,6) 1249 10.1 (9.51,10.6)
C00-96 All sites 1898 1.89 (1.81,1.98) 3725 1.91 (1.84,1.96)
C00-967 All, exc. skin 1088 1.22 (1.15,1.30) 2354 1.33 (1.28,1.39)
C00-968 All, exc. SCC 1183 1.23 (1.16,1.30) 2476 1.31 (1.25,1.36)
  1. 1The number of cancer cases in the SIR-analyses differs slightly from that used in the logistic regression analyses as the data were extracted on different dates from the Cancer Registry of Norway. 2The cancer sites are not mutually exclusive. 3Observed number of cases. 4Includes ICD-10 codes C00-06 and C09-14. 5Central nervous system tumors. 6Includes ICD-10 codes C15-17, C22-24, C26, C30-32, C37, C39-41, C45-49, C60, C62-63, C69, C74-76, C80, C88, C90. 7All sites except C43 and C44. 8All sites except C44.