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Figure 5 | BMC Cancer

Figure 5

From: The pemetrexed-containing treatments in the non-small cell lung cancer, is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis

Figure 5

Subgroup analysis by TS detection method. In IHC subgroup, objective response rate in TS -/low expression patients was significantly higher than that in TS +/high expression patients (OR = 0.44; 95% CI, 0.27–0.71; p = 0.0009). And in Real-time reverse transcriptase PCR subgroup, there was a trend that TS -/low predicted better objective response rate, but the difference did not reached statistical significance (OR = 0.52; 95% CI,0.18-1.54 p = 0.24).

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