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Figure 4 | BMC Cancer

Figure 4

From: The pemetrexed-containing treatments in the non-small cell lung cancer, is -/low thymidylate synthase expression better than +/high thymidylate synthase expression: a meta-analysis

Figure 4

Subgroup analysis by chemotherapy regimen. In the subgroup of the patients treated with pemetrexed plus cisplatin or carboplatin, overall objective response rate in TS -/low patients was significantly higher than that in TS +/high patients (OR = 0.27, 95% CI 0.10–0.70, p = 0.007). For the patients treated with pemetrexed monotherapy or pemetrexed plus gemcitabine, the overall objective response rate for patients with -/low TS expression was significantly higher than that for patients with +/high TS expression(OR = 0.54, 95% CI 0.33–0.91, p = 0.02).

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BMC Cancer

ISSN: 1471-2407

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