Table 2 List of miRNAs significantly differentially expressed (corrected p-value < 0.05 and foldchange >2) between breast cancer and normal serum in the discovery cohort

hsa-miR-186

6.1

<0.0001

hsa-miR-484

5.5

<0.0001

hsa-miR-29a

5.0

0.0001

hsa-miR-425

4.9

<0.0001

hsa-miR-454

4.0

<0.0001

hsa-miR-574-3p

3.9

<0.0001

hsa-miR-140-3p

3.2

<0.0001

hsa-miR-222

3.1

<0.0001

hsa-let-7b

3.0

0.0002

hsa-miR-483-5p

2.8

0.0157

has-miR-155

2.4

0.0078

Roth et al. [24] and Wang et al. [25] found over-expression of miR-155 in breast cancer patients

hsa-miR-126

2.3

<0.0001

Wang et al. [25] found under-expression of miR-126 in breast cancer patients

hsa-miR-146b-5p

2.3

0.0001

hsa-miR-320

2.3

<0.0001

hsa-miR-191

2.3

0.0002

hsa-miR-342-3p

2.2

0.0003

hsa-miR-486-5p

2.0

0.0003