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Table 1 Clinical characteristics of the healthy volunteers, breast cancer patients and pathological characteristics of breast cancers in the discovery and validation cohorts as well as tissue samples used

From: MicroRNA-484 is more highly expressed in serum of early breast cancer patients compared to healthy volunteers

 

Discovery cohort

Discovery cohort normal

Validation cohort

Validation cohort normal

Tissue

Number of patients

39

10

98

25

12

Age (mean ± SD)

58 ± 16

60 ± 6

55 ± 12

57 ± 12

59 ± 16

Subtype of cancer

39 IDC

 

89 IDC 9 ILC

 

12 IDC

Size of invasive cancer (mm)

30.5 ± 25.2

 

26.4 ± 14.5

 

43.1 ± 35.5

Lymph node negative (%)

19 (48.7%)

 

40 (44.9%)

 

5 (41.7%)

Number of positive axillary lymph nodes

3.0 ± 6.4

 

2.8 ± 5.4

 

5.6 ± 10.2

ER positive

28 (71.8%)

 

69 (77.5%)

 

8 (66.7%)

PR positive

22 (56.4%)

 

69 (77.5%)

 

6 (50.0%)

HER2 positive

6 (15.4%)

 

18 (20.2%)

 

3 (25.0%)

  1. Abbreviations: IDC = invasive ductal carcinoma, ILC = invasive lobular carcinoma.