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Table 5 Publications on acute toxicity of radiotherapy of the prostate bed with or without pelvic irradiation

From: Helical intensity-modulated Radiotherapy of the Pelvic Lymph Nodes with Integrated Boost to the Prostate Bed - Initial Results of the PLATIN 3 Trial

  Acute grade 1 Acute grade 2 Acute grade 3 Acute grade 4
   GI GU GI GU GI GU GI GU
Bellavita et al. [13] 3D-CRT prostate bed 66.6 Gy 48.9% (G1/2) - - - 1.1% - 0% 0%
Current trial IMRT WPRT 51 Gy + boost prostate bed 68 Gy 67.5% 22.5% 22.5% 22.5% 0% 0% 0% 0%
Alongi et al.[14] IMRT WPRT 50.6 Gy + boost prostate bed 70–72.5 Gy - - 3.3% 6.6% 0% 0% 0% 0%
Deville et al.[15] IMRT WPRT 45 Gy Gy + boost prostate bed 70.2 Gy 31% 67% 61% 22% 0% 0% 0% 0%
Alongi et al.[14] 3D-CRT WPRT 50.1 Gy + boost prostate bed 72.1 Gy - - 8.6% 12.3% 0% 0% 0% 0%
Aizer et al.[16] 3D-CRT WPRT 45 Gy + IMRT boost prostate 75.6 Gy 75% 44.1% 17.6% 33.8% 1.5% 10.3% 0% 0%
Roach et al.[4] 3D-CRT WPRT 45 Gy + boost prostate 70.2 Gy - - - - 2.6% (G3/4) 3.9% (G3/4) 0% 0%
Liu et al.[17] 2D WPRT 45 Gy + boost prostate 72 Gy 12.2% 10.9% 1.3% 3.8% 0.6% 0.6% 0% -
  1. Published data on acute toxicity of adjuvant 3D conformal radiotherapy (3D-CRT) of the prostate bed (regular print), adjuvant intensity-modulated radiotherapy (IMRT) of the whole pelvis (WPRT) with a boost to the prostate bed (bold print) and definitive or adjuvant 3D-CRT WPRT with a boost to the prostate or prostate bed (italic print). (GI = gastrointestinal, GU = genitourinary).